Liverpool maintained their Merseyside stranglehold over Everton with a 5-2 win over their rivals to remain eight points clear at the top of the Premier League.
In one of the showpiece fixtures of the season under the lights at Anfield, the game lived up to its billing in an extraordinary first half which saw six goals scored.
Sadio Mane laid on two sublime assists for Divock Origi (6) and Xherdan Shaqiri (17) - who were both handed starts in place of Mohamed Salah and Roberto Firmino - to put Liverpool in control.
Michael Keane (21) hit back for Everton but two more special Liverpool goals from Origi (31) and Mane (44) restored the three-goal cushion for just two minutes before Richarlison (45+2) made it 4-2 just before the break.
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Georginio Wijnaldum wrapped it up late on (90) as the Everton fans streamed out of Anfield.
It is now 20 games unbeaten for Liverpool against Everton in all competitions and under-pressure Toffees boss Marco Silva now sees his team in the relegation zone after losing nine of their last 13 Premier League games.
How Reds left Toffees in a sticky situation.
Jurgen Klopp sprang a surprise in his team selection by omitting both Salah and Firmino and handing a first Premier League start since January 30 to Shaqiri.
How the teams lined up
Liverpool took just six minutes to set the tone for a thrilling opening half. Mane's brilliant pass saw Origi scamper through on goal and he rolled the ball past Jordan Pickford.
Trent Alexander-Arnold then picked out Mane with an amazing cross-field pass and he reversed a wonderful pass to Shaqiri who clipped home.
Keane scored from close range minutes later after Dejan Lovren failed to clear an Alex Iwobi cross, but Lovren redeemed himself by setting up Liverpool's third.
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His 40-yard pass was expertly controlled with one touch and lifted over Pickford by a ruthless Origi, who was taking his chance in the absence of Firmino.
Silva switched to a 4-4-2 formation, but it made no difference as Liverpool kept on coming.
Alexander-Arnold raced down the left and found Mane in space with a perfect ball. The striker swept home from the edge of the box with his left foot.
Everton were on the verge of crumbling but responded immediately when Richarlison's diving header found the back of the net to restore some hope.
The second half did not hit the heights of the first with Liverpool managing the game and Everton looking devoid of any confidence. Mane missed two one-on-one chances before Wijnaldum sent the home fans home happy by scoring as the clock ticked into stoppage time.
That goal also saw the Everton fans flooding to the exits as "going down" was chanted in their direction by the Anfield faithful, whose team are now unbeaten in their last 32 Premier League games (W27 D5), their longest run without defeat in top-flight history.
'Everton arguing among themselves'
Analysis: Sky Sports News' Vinny O'Connor
If Silva's instruction to his players was to keep it tight, the gameplan was ripped up early on.
Despite five changes, Liverpool started fluidly, while Everton, in contrast, looked uncertain. It said a lot that the Everton players were arguing among themselves, highlighting how unsure of their roles they appeared to be.
Other teams haven't fared well when they've gone with three centre-backs away at Anfield and Everton went the same way. Liverpool happily exploited them. When Silva switched to a back four after half an hour, with Bernard replacing Djibril Sidibe and Mason Holgate switching to right-back, it appeared that even the Everton manager was acknowledging he'd made a mistake starting with a back five.
Everton showed some fight, but, despite their two goals, they never gave the impression they felt they could really go on and get back into the game. Silva has been unlucky with injuries in midfield, but tonight will raise further questions, if not action, over his future.
Meanwhile, Klopp has maintained Liverpool's advantage at the top while managing the workload of some of his key players.
Opta statsKlopp has won 100 of his 159 Premier League games, he is the second fastest manager to reach 100 wins in the competition, after Jose Mourinho (142 games). In fact, he is the fastest Liverpool manager to 100 wins in top-flight history.Everton find themselves in the relegation zone after playing at least 15 Premier League matches for the first time since April 10th 1999 (after 32 games).Silva is the first Everton manager to concede five league goals against Liverpool in a single match since Howard Kendall in November 1982 (0-5 against Bob Paisley's Liverpool).Origi has scored five Premier League goals against Everton; only Robbie Fowler (6) and Steven Gerrard (9) have scored more PL goals for Liverpool in the Merseyside derby. Indeed, Origi has now scored in all four matches against Everton for Liverpool at Anfield (five goals).What's next?
Next up for Liverpool is a visit to Bournemouth on Saturday followed by a trip to Red Bull Salzburg on Tuesday in the Champions League. Meanwhile, Everton host Chelsea on Saturday lunchtime.
© GettySadio Mane celebrates with team-mates after scoring Liverpool's fourth goal