Arctic Monkeys will headline the Pyramid Stage at Glastonbury on Friday night after the band was forced to cancel a gig because frontman Alex Turner was struck down by illness.
The festival's co-organiser Emily Eavis confirmed the Sheffield group will perform in front of crowds after their set was thrown into question earlier this week.
On Wednesday, the band was scheduled to appear at Marlay Park in Dublin but the show was cancelled two days previously because Alex Turner had acute laryngitis.
Broadcasting from the grounds of the festival at Worthy Farm, Zoe Ball asked during her BBC Radio 2 show if the band were still set to play, and Eavis replied "they're on", which was welcomed with applause.
"It was a little bit close there for a minute and we were thinking about whether we should have a serious back-up plan in place, but no, thankfully they're on, so that's great," she added.
It will be the band's third time headlining the festival after topping the bill on 2007 and 2013.
Since the start of the year, they have performed hits across Australia, Asia and the UK from their back catalogue including I Wanna Be Yours, 505 and Do I Wanna Know?
They performed three shows at the Emirates stadium in London from Friday to Sunday last week before they had to announce that Turner was under doctor's orders to rest.
Eavis also appeared to accidentally confirm rumours that Rick Astley and Blossoms will play a secret set this weekend.
When asked about if their set was confirmed, she said: "Yep" before catching herself and asking if the show was being broadcast live.
The other major rumour of the day is in relation to a mystery band named The Churnups who are listed to perform ahead of rock duo Royal Blood and Arctic Monkeys, with speculation that could be a cover name for Foo Fighters.
Addressing the rumblings, Eavis said: "To be honest, I think there's a lot of rumours that are circulating about The Churnups one of which is true. I don't think I can completely confirm but it's coming soon.
"But this is a huge, huge, huge, huge surprise and we have kept this secret for so long, just me and (her husband) Nick, we didn't even tell the kids we were like 'Nobody can know this' and I think it's going to be extraordinary later."
Hozier has also confirmed on Friday morning that he will be the surprise act at 7.30pm on the Woodsies stage, previously named the John Peel stage.
The Irish singer-songwriter, full name Andrew Hozier-Byrne, said he is "thrilled" to be performing at the festival again in a "not-so-secret set" on Friday evening.
The third day of the festival in Pilton, Somerset, will also host film screenings, theatre and circus performances and a debate titled Solidarity With Iran, which will include British-Iranian charity worker Nazanin Zaghari-Ratcliffe, who was imprisoned by Tehran for six years.
Meanwhile, the Met Office has forecast that Glastonbury will have mainly "dry and bright" weather on Friday, with temperatures hitting around 25C during the day.
In a statement, a spokesperson for the national weather service said: "The weather is set fair for much of the weekend at Glastonbury Festival with only a small chance of a shower.
"Friday and Saturday should see a good deal of dry, bright weather with some sunny spells, albeit hazy at times, with highs in the mid-20s, with some warm nights to follow once the sun goes down.
"Sunday will see some warm sunshine at first, though a few showers are possible through the afternoon, though these will be hit and miss in nature.
"Conditions look set to freshen up from Monday as temperatures fall closer to average."
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