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Roy Hodgson's men enter tonight's showdown with a psychological edge, knowing they have already pulled off a Premier League victory over Manchester United once this season.
United started the season a week late due to their overhanging Europa League campaign, and suffered a humiliating loss to the Eagles on their own patch.
It sparked a miserable run for Ole Gunnar Solskjaer's men, before the quickly got back on track and made a surge for the top of the table. Victory tonight, however, is crucial if the Red Devils are to have any hope of stopping neighbours Manchester City running away with the title.
Follow Sportsmail's Danny Gallagher for live EPL coverage of Crystal Palace vs Manchester United, including scoreline, lineups and build-up.
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