Australian Test players Mitchell Starc and Steve Smith have both been withdrawn from NSW's Sheffield Shield clash against Victoria at Bankstown Oval.
Starc has withdrawn from the squad after his father, Paul, lost his battle with cancer on Tuesday.
The left-arm quick also sat out two of Australia's T20 matches against India last year due to personal reasons.
His wife and fellow cricketer Alyssa Healy will also miss the NSW Breakers' WNCL clash against Tasmania.
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Starc took one wicket in NSW's last match, their Sheffield Shield loss against Victoria at the SCG last week.
Test batsman Steve Smith will miss the match at Bankstown due to an ongoing elbow injury.
"I have had some pain in my elbow that's gradually worsened since the Test against India at the SCG and it requires some rest and rehab," Smith said.
"I am hoping I will be right to travel with the Blues to Adelaide for our games down their next week but we will have to see how it responds to treatment."
The Test pair will be replaced by Liam Hatcher and Jason Sangha in NSW's 13-man squad.
Nathan Lyon, who passed 600 first-class wickets in NSW's last match against Victoria, says that the squad will come together to support Starc in this tough time.
"It's a tough time for Mitch," Lyon said.
"But he knows he's got all our love and all our support, not just me but everyone here at NSW Cricket and the cricket community as well.
"We'll throw our arm around him and get around him."
Lyon came out of the match at the SCG with the best figures of his Sheffield Shield career, 10/78 for the match including 6/21 in the first innings.
For the off-spinner, it's about continuing that form in this unprecedented run of domestic games.
"It's always nice to go back out there for NSW and perform well," Lyon said.
"That's what our aim is to do and go out there and play our best cricket.
"It's really nice being at home, to be honest with you and to put our pure focus in the rest of the Shield season.
"It'll work out that I'll play the whole Shield season and I haven't done that, ever.
"It's a really good opportunity and NSW, we're a strong squad, so make sure we go out and play a positive brand of cricket."